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Then most parents will state what they are doing, e.g. Because dissolved oxygen is not confined to a hemoglobin molecule, it can go wherever "body water goes" and therefore reach 'deeper tissues' more easily and more consistently than ever before Because no test is able to predict which child may and which child may not respond to extra pressure and/or extra oxygen (in contrast to excessive oxygen), I let nature take its course and prescribe a clinical trial of HBOT for all my children Though I let "nature take its course", I would not consider prescribing or administering HBOT to children with autism unless there was good scientific evidence to support its use.
"we're using 1.5, 1.75, or 2.0 atmospheres in a hard chamber with 100% oxygen, or we're using a soft chamber (also referred to as a mild chamber) at 1.3 atmospheres 'with or without a mask' to which 'concentrated oxygen' is be supplied at concentrations varying from 24% to 70%." Conventional wisdom states that unless one receives HBOT in a hard chamber with 100% oxygen at atmospheric pressures greater than 1.5 ATA, little or no benefit will be seen. Fortunately such evidence does exist, the body of which continues to accumulate, and the mechanisms of action by which HBOT may work for children with autism, as described below, may already be outdated by the time you read this.
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However, there is no reason to believe that even mildly increased oxygen tensions may inhibit viral activity and/or make the host less hospitable to chronic viral inhabitation.
Therefore, whenever inflammation brings more fluid to a region of the body that is comprised of solid tissue and hollow blood vessels, the first thing to happen is that the hollow blood vessel lumens will be compressed and deliver fewer red cells carrying oxygen to the area.
Once inflammation is reduced the secondary vascular narrowing is improved allowing increasing amounts of red blood cells carrying oxygen to reach the hypoxic areas and SPECT scans will once again "light up" turning from blue to yellow.
Efrain Olszewer has pre- and post-angiograms documenting collateral circulation beginning as early as ten to twenty hours after initiating hyperbaric therapy for cerebral vascular disease and peripheral arteriosclerosis at pressures lower than 1.3 ATA It is known that one of the problems children with autism have is decreased blood flow to the brain (cerebral hypoperfusion).
Therefore is has been speculated that angioneogenesis is the way that HBOT helps autism However, though angioneogenesis may be one mechanism by which children with autism are helped by HBOT, angioneogenesis may not be the primary mechanism by which HBOT works The amount of cerebral hypoperfusion in autistics compared to controls is about 8%, so a small increase in oxygen delivery may be all that is needed to overcome this deficit and show clinical benefit.
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Many children with autism have increased amounts of abnormal bacteria and yeast in their gastrointestinal tracts These same children have shown clinical improvements when this overgrowth phenomenon is treated with antibiotics, either by natural agents or pharmaceuticals.